1. 谷歌官方已經(jīng)給出了相關(guān)的文檔，參照網(wǎng)上搜索的資料，首先，我的問題是：

Error:Execution failed for task ':duchazhushou:dexRelease'.
> com.android.ide.common.internal.LoggedErrorException: Failed to run command:
    C:\Users\jeff\AppData\Local\Android\sdk\android-sdk\build-tools\21.1.1\dx.bat --dex --output D:\dev\android\Duchazhushou_TDT\duchazhushou\build\intermediates\dex\release --input-list=D:\dev\android\Duchazhushou_TDT\duchazhushou\build\intermediates\tmp\dex\release\inputList.txt
Error Code:
Output:
    UNEXPECTED TOP-LEVEL EXCEPTION:
    com.android.dex.DexIndexOverflowException: method ID not in [0, 0xffff]: 65536
        at com.android.dx.merge.DexMerger$6.updateIndex(DexMerger.java:502)
        at com.android.dx.merge.DexMerger$IdMerger.mergeSorted(DexMerger.java:277)
        at com.android.dx.merge.DexMerger.mergeMethodIds(DexMerger.java:491)
        at com.android.dx.merge.DexMerger.mergeDexes(DexMerger.java:168)
        at com.android.dx.merge.DexMerger.merge(DexMerger.java:189)
        at com.android.dx.command.dexer.Main.mergeLibraryDexBuffers(Main.java:454)
        at com.android.dx.command.dexer.Main.runMonoDex(Main.java:302)
        at com.android.dx.command.dexer.Main.run(Main.java:245)
        at com.android.dx.command.dexer.Main.main(Main.java:214)
        at com.android.dx.command.Main.main(Main.java:106)

2. 在項目的build.gradle文件的dependencies 節(jié)中添加分包設(shè)置：

dependencies { 
... 
   compile 'com.android.support:multidex:' 
   ... 
}

3. 通過在defaultConfig節(jié)中設(shè)置multiDexEnabled標簽為true，開啟multi-dexing支持:

defaultConfig { 
   ... 
multiDexEnabled true 
... 
}

4. Application繼承android.support.multidex.MultiDexApplication，或直接在AndroidManifest.xml文件的Application聲明中添加:

android:name="android.support.multidex.MultiDexApplication"

5. 重新build。

參考來源