library(reshape)

library(eulerr)

MIIZygoteup <- read.table("upgene.txt")

MIIRIP<-read.table("MII-RIPgene.txt")

MIIZygoteup<-MIIZygoteup[,1]

MIIRIP<-MIIRIP[,1]

s4<-list(a=MIIZygoteup,b=MIIRIP)

news4<-rename(s4,c(a="MII → Zygote up gene",b=" MII RIP"))

plot(euler(news4, shape = "ellipse"), quantities = TRUE)