4E-BP1 4E-binding protein 1
5′TOP 5′ terminal oligopyrimidine
AMPK AMP-activated protein kinase
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATG autophagy regulated protein
ATM ataxia telangiectasia mutated
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CaMKKbeta calmodulin-dependent protein kinase kinase β
CMA chaperon-mediated autophagy
DYRK3 dual specificity tyrosine-phosphorylation-regulated kinase 3
eIF2α eukaryotic translation initiation factor 2α
eIF4B eukaryotic translation initiation factor 4B
eIF4E eukaryotic translation initiation factor 4E
ER endoplasmic reticulum
FIP200 FAK family kinase-interacting protein of 200 kDa
FLCN folliculin
FMRP fragile X mental retardation protein
FoxO1/3A forkhead box O1/3A
G3BP Ras-GTPase activating protein SH-3 domain binding protein
GAP GTPase-activating protein
GCN2 general control nonderepressible 2
GLUT4 glucose transporter 4
Grb10 growth factor receptor-bound protein 10
GSK glycogen synthase kinase
HIF hypoxia inducible factor
hnRNP-A1 heterogeneous nuclear ribonucleoprotein A1
HRI hemin-regulated inhibitor
HSF1 heat shock factor protein 1
Hsp70 70 kDa heat shock protein
IR insulin receptor胰島素受體
Ire1 inositol-requiring protein 1
IRES internal ribosomal entry sites
IRS insulin receptor substrate
JNK c-Jun NH(2)-terminal kinase
LARP1 La-related protein 1
LDH lactate dehydrogenase
MAPK mitogen activated protein kinase
MAM mitochondria線粒體-associated ER membrane
mSin1 mammalian stress-activated protein kinase interacting protein 1
mtDNA mitochondrial DNA
mTOR mammalian target of rapamycin意思是雷帕霉素在哺乳動(dòng)物中的靶點(diǎn)蛋白。由于不只是存在于哺乳動(dòng)物當(dāng)中，所以mammalian更改為mechanistic
mTORC1 mTOR complex 1
mTORC2 mTOR complex 2
NFL negative feedback loop
NOX NADPH oxidase
Nrf2 nuclear factor erythroid 2-like 2
PABP1 polyadenylate-binding protein 1
PDK1 3-phosphoinositide-dependent kinase-1
PERK protein kinase RNA-like ER kinase
PI3K phosphatidylinositol 3-kinases
PIP2 phosphatidylinositol-3,4-biphosphate
PIP3 phosphatidylinositol-3,4,5-triphosphate
PKR double-stranded RNA activated protein kinase
PPP pentose phosphate pathway
PTEN phosphatase and tensin homolog
R5P ribose-5-phosphate
raptor regulatory associated protein of mTOR
RACK1 signaling scaffold protein receptor of activated protein kinase C 1
REDD1 regulated in development and DNA damage responses 1
rheb ras-homolog-enriched-in-brain
rictor rapamycin-insensitive companion of mTOR
ROS reactive oxygen species活性氧
SGs stress granules
S6K S6 kinase
SREBP sterol regulatory element-binding protein
TCA cycle tricarboxylic acid cycle循環(huán)三羧酸循環(huán)
TIA-1 T cell intracellular antigen 1
TIAR TIA-1-related protein
TNFα tumor necrosis factor alpha
TRAF2 TNF receptor-associated factor 2
TRB3 tribbles homolog 3
TSC1 hamartin (tuberous sclerosis 1 protein)
TSC2 tuberin (tuberous sclerosis 2 protein)
ULK1 unc-51-like kinase
uORF upstream open reading frame
UPR unfolded protein response
USP10 ubiquitin-specific protease 10
VEGF vascular endothelial growth factor