使用方法參考大佬寫的就行 http://www.itdecent.cn/p/dfe35a2a02d4
作者總結(jié)了一些pathway的LR pair，我們可以直接拿來使用。
LR_database
加載進去是這樣的
image.png
幾個pathway的LR數(shù)量如下
image.png
可以使用這些分類信息進行文章crosstalk bubble plot的展示，比如這篇文章
image.png
The ligand-receptor pairs in CellChat retrieved from previous studies were divided into four groups including, cytokine/chemokine, immune checkpoint, growth factor, and others [37]. The crosstalk between cell analyses conducted via “CellChat” was as follows: (1) “createCellChat” function was applied to create “CellChat” object; (2) the “computeCommunProb,” “computeCommunProbPathway,” and “aggregateNet” functions were adopted to infer the cellular communication network; (3) “netVisual_aggregate,” “netVisual_signalingRole,” and “netVisual_bubble” were adopted to visualize crosstalk among cells.
文章地址：https://doi.org/10.1016/j.ebiom.2021.103459
