發(fā)簡信
IP屬地：巴登-符騰堡
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酮體代謝1. 酮體代謝途徑 第一階段：肝臟中的酮體生成 (Ketogenesis) 當(dāng)人體處于饑餓、長時運(yùn)動或某些病理狀態(tài)（如心力衰竭）時，肝臟開始大量...
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Redox regulation一、Redox regulation Redox signaling, a mode of signal transduction that i...
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色氨酸代謝通路色氨酸（Tryptophan）進(jìn)入人體后，會同時走“宿主代謝通路”和“腸道細(xì)菌代謝通路”，最終生成一系列不同的生物活性分子。 Tryptopha...
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鐵死亡通路機(jī)制：當(dāng)細(xì)胞膜上的多不飽和脂肪酸（PUFA）被鐵和氧化反應(yīng)持續(xù)“燒壞”，而細(xì)胞又來不及用谷胱甘肽/GPX4把這些損傷清掉時，就會發(fā)生鐵死亡。 一...
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文獻(xiàn)學(xué)習(xí)133--Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction1. FMO3 Induces FoxO1 via Its Product, TMAO FMO3在體內(nèi)的作用機(jī)制復(fù)雜，難以進(jìn)行機(jī)制研究。因此作者...
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文獻(xiàn)學(xué)習(xí)132--ISR Couples Mitochondrial Protein Translation With Oxidative Stress Control整合應(yīng)激反應(yīng) 1. Ischemia/Reperfusion Is Associated With Decreased Protein Synt...
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文獻(xiàn)學(xué)習(xí)131--IDO1 inhibitors block septic cytokine storm by suppressing the IDO1-AHR-CYP1A1 axis1. IDO1 was closely associated with the cytokine storm phase of sepsis I...
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文獻(xiàn)學(xué)習(xí)130--內(nèi)皮細(xì)胞IDO1通過Kyn調(diào)節(jié)心梗的心臟功能1. Upregulation of IDO Activity After MI Alters Cardiac Function and Rem...
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文獻(xiàn)學(xué)習(xí)129--GDF15 antagonism limits severe heart failure and prevents cardiac cachexia1. Mice lacking functional PPP1R15A exhibit left ventricular dilated car...